| 1. | The risk for death may be greater with conventional antipsychotics than with atypical antipsychotics
运用传统的抗精神病药物的患者较非标准运用抗精神病药物具有更高的死亡风险。 |
| 2. | Relative to atypical antipsychotic use , conventional antipsychotic use was associated with a higher risk for death at all time points
相对于非标准运用抗精神病药物而言，传统的抗精神病药物运用在各个时间点上均与死亡高风险性相关。 |
| 3. | It appears that to the extent that studies mimic " real world " conditions they fail to support the cost - effectiveness of the atypical antipsychotics
这表明，在某种程度上，当研究模仿“真实世界”情况时，并不支持非典型抗精神病药物的费用-有效性。 |
| 4. | Conclusions : atypical antipsychotic use is associated with an increased risk for death compared with nonuse among older adults with dementia
结论：在老年痴呆患者中，非标准地运用抗精神病药物患者对比不运用抗精神病药物患者而言与死亡风险性增加相关。 |
| 5. | The wide scale use of expensive atypical antipsychotic medications has led to a dramatic increase in the proportion of direct costs schizophrenia being allocated for medications
昂贵的非典型抗精神病药物的广泛使用，导致分摊到精神分裂症药物治疗直接费用的比例急剧升高。 |
| 6. | Although there is evidence that the atypical antipsychotic , clozapine , may lead to cost savings in patients with refractory schizophrenia the cost - effectiveness of the other atypical antipsychotics remains in question
尽管有证据表明，非典型抗精神病药物氯氮平，可使难治性精神分裂症患者节省费用，而其它非典型抗精神病药物的费用-效能仍存疑问。 |
| 7. | Atypical antipsychotics ( aap ) are utilized extensively now a days to treat not only schizophrenia but also for mood disorders a mood stabilizer because of the effect and the safety for positive and negative symptoms of schizophrenia and the affective symptoms of affective disorders especially bipolar disorders
摘要目前非典型抗精神病药应用越来越广泛，有逐渐取代典型抗精神病药的趋势，不但用于精神分裂症的治疗，而且作为心境稳定剂治疗情感障碍。 |
| 8. | New use of atypical antipsychotics was associated with a statistically significant increase in the risk for death at 30 days compared with nonuse in both the community - dwelling cohort ( adjusted hazard ratio , 1 . 31 [ 95 % ci , 1 . 02 to 1 . 70 ] ; absolute risk difference , 0 . 2 percentage point ) and the long - term care cohort ( adjusted hazard ratio , 1 . 55 [ ci , 1 . 15 to 2 . 07 ] ; absolute risk difference , 1 . 2 percentage points )
非标准抗精神病药物的新用法与未运用抗精神病药物中用药30日后的死亡风险性统计学上的显著增加相关，其中在社区居住队列组别（校正危害比为1 . 31 ， 95 %可信区间为1 . 02至1 . 70 ，绝对风险差异为0 . 2百分点）中和在长期护理组（校正危害比为1 . 55 ， 95 %可信区间为1 . 15至2 . 07 ，绝对风险差异为1 . 2百分点）中都如此。 |
